NAPLES (Napoli) - Southern Italy’s largest city, located in the Region of Campania, is famous for its intoxicating mix of Old World charm and modern grit. This is one of the oldest cities in Europe, with enough art, architecture, and archeology to hold its own against other metropolitan cities. It is situated on the Gulf of Naples, on the western coast of southern Italy, in the shadow of Mount Vesuvius (Vesuvio), the only active volcano in mainland Europe.